Anti-LAMTOR3 Polyclonal Antibody - SAlexa Fluor 647
Cat: K111215P - SAlexa Fluor 647
Summary:
| 【Product name】：Anti-LAMTOR3 Polyclonal Antibody - SAlexa Fluor 647 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：8649 | 【Swiss Prot】：Q9UHA4 |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human LAMTOR3 | |
| 【Public Immunogen Range】：1-125aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2.
Verified picture: