Anti-GRIK1 Polyclonal Antibody - SAlexa Fluor 350
Cat: K111316P - SAlexa Fluor 350
Summary:
| 【Product name】：Anti-GRIK1 Polyclonal Antibody - SAlexa Fluor 350 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：2897 | 【Swiss Prot】：P39086 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human GRIK1 | |
| 【Public Immunogen Range】：95-145/918aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to alter the properties of ion flow. Alternative splicing, resulting in transcript variants encoding different isoforms, has been noted for this gene.
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