Anti-ORC5 Polyclonal Antibody
Cat: K111340P
Summary:
| 【Product name】：Anti-ORC5 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5001 | 【Swiss Prot】：O43913 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000.;IHC 1:100-300. | |
| 【Immunogen】：Recombinant protein of human ORC5 | |
| 【Public Immunogen Range】：83-427aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Verified picture:
Western blot analysis with ORC5 antibody diluted at 1:2000;Lane: A431,Human lung cancer.
Immunohistochemistry of paraffin-embedded Human breast cancer with ORC5 antibody diluted at 1:200.