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Anti-AP4M1 Polyclonal Antibody - Cy3.5
Cat: K111353P - Cy3.5
Summary:
【Product name】:Anti-AP4M1 Polyclonal Antibody - Cy3.5 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:9179 【Swiss Prot】:O00189
【Tested applications】:WB
【Recommended dilution】:WB 1:1000-3000.
【Immunogen】:Recombinant protein of human AP4M1
【Public Immunogen Range】:121-360aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways (PubMed:10436028, PubMed:11139587, PubMed:10066790, PubMed:11802162, PubMed:20230749). AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system (PubMed:11139587, PubMed:20230749). It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons (By similarity). Within AP-4, the mu-type subunit AP4M1 is directly involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos (PubMed:10436028, PubMed:11139587, PubMed:26544806, PubMed:20230749). The adaptor protein complex
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