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Anti-MC1R Polyclonal Antibody - Cy3.5
Cat: K111478P - Cy3.5
Summary:
【Product name】:Anti-MC1R Polyclonal Antibody - Cy3.5 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:4157 【Swiss Prot】:Q01726
【Tested applications】:WB
【Recommended dilution】:WB 1:1000-3000.
【Immunogen】:A synthetic peptide of human MC1R
【Public Immunogen Range】:267-317/317aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Receptor for MSH (alpha, beta and gamma) and ACTH (PubMed:1325670, PubMed:8463333, PubMed:1516719, PubMed:11442765, PubMed:11707265). The activity of this receptor is mediated by G proteins which activate adenylate cyclase (PubMed:1325670, PubMed:11707265, PubMed:16463023, PubMed:19737927). Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes (PubMed:31097585).
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