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Anti-CARD14 Polyclonal Antibody - SAlexa Fluor 660
Cat: K111560P - SAlexa Fluor 660
Summary:
【Product name】:Anti-CARD14 Polyclonal Antibody - SAlexa Fluor 660 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Octanoic acid-ammonium sulfate precipitation
【Gene ID】:79092 【Swiss Prot】:Q9BXL6
【Tested applications】:IHC
【Recommended dilution】:IHC 1:50-200.
【Immunogen】:A synthetic peptide of human CARD14
【Public Immunogen Range】:705-755/1004aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Acts as a scaffolding protein that can activate the inflammatory transcription factor NF-kappa-B and p38/JNK MAP kinase signaling pathways. Forms a signaling complex with BCL10 and MALT1, and activates MALT1 proteolytic activity and inflammatory gene expression. MALT1 is indispensable for CARD14-induced activation of NF-kappa-B and p38/JNK MAP kinases. May play a role in signaling mediated by TRAF2, TRAF3 and TRAF6 and protects cells against apoptosis.
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