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Anti-CD101 Polyclonal Antibody - RBITC
Cat: K111566P - RBITC
Summary:
【Product name】:Anti-CD101 Polyclonal Antibody - RBITC 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:9398 【Swiss Prot】:Q93033
【Tested applications】:WB ELISA IHC ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:A synthetic peptide of human CD101
【Public Immunogen Range】:325-375/1021aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells. May be a marker of CD4+ CD56+ leukemic tumor cells.
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