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Anti-Phospho-AMPKα1-T183/AMPKα2-T172 Polyclonal Antibody
Cat: K009990P
Summary:
【Product name】:Anti-Phospho-AMPKα1-T183/AMPKα2-T172 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:5562/5563 【Swiss Prot】:Q13131/P54646
【Tested applications】:WB
【Recommended dilution】:WB 1:500-2000
【Immunogen】:A phospho specific peptide corresponding to residues surrounding T172 of human AMPKα.
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
AMPK belongs to the ser/thr protein kinase family. Alpha subunit is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways.
Verified picture:
Western blot analysis with Phospho-AMPKα1-T183/AMPKα2-T172 antibody diluted at 1:1000;Lane: 293T C6.