Anti-CYP2C18 Polyclonal Antibody - Cy3
Cat: K111710P - Cy3
Summary:
| 【Product name】：Anti-CYP2C18 Polyclonal Antibody - Cy3 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1562 | 【Swiss Prot】：P33260 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human CYP2C18 | |
| 【Public Immunogen Range】：20-370aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
A cytochrome P450 monooxygenase involved in retinoid metabolism. Hydroxylates all trans-retinoic acid (atRA) to 4-hydroxyretinoate and may modulate atRA signaling and clearance. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).
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