Anti-MRAP2 Polyclonal Antibody - SAlexa Fluor 680
Cat: K111711P - SAlexa Fluor 680
Summary:
| 【Product name】：Anti-MRAP2 Polyclonal Antibody - SAlexa Fluor 680 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：112609 | 【Swiss Prot】：Q96G30 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-3000. | |
| 【Immunogen】：Recombinant protein of human MRAP2 | |
| 【Public Immunogen Range】：68-205aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Modulator of melanocortin receptor 4 (MC4R), a receptor involved in energy homeostasis. Plays a central role in the control of energy homeostasis and body weight regulation by increasing ligand-sensitivity of MC4R and MC4R-mediated generation of cAMP (By similarity). May also act as a negative regulator of MC2R: competes with MRAP for binding to MC2R and impairs the binding of corticotropin (ACTH) to MC2R. May also regulate activity of other melanocortin receptors (MC1R, MC3R and MC5R); however, additional evidence is required in vivo.
Verified picture: