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Anti-NUDT1 Polyclonal Antibody - HRP
Cat: K111727P - HRP
Summary:
【Product name】:Anti-NUDT1 Polyclonal Antibody - HRP 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:4521 【Swiss Prot】:P36639
【Tested applications】:IHC
【Recommended dilution】:WB 1:500-2000. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200
【Immunogen】:Recombinant protein of human NUDT1
【Public Immunogen Range】:1-180aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Antimutagenic. Plays a redundant role in sanitizing oxidized nucleotide pools, such as 8-oxo-dGTP pools. Acts as a sanitizing enzyme for oxidized nucleotide pools, thus suppressing cell dysfunction and death induced by oxidative stress. Hydrolyzes 8-oxo-dGTP, 8-oxo-dATP and 2-OH-dATP, thus preventing misincorporation of oxidized purine nucleoside triphosphates into DNA and subsequently preventing A:T to C:G and G:C to T:A transversions. Able to hydrolyze also the corresponding ribonucleotides, 2-OH-ATP, 8-oxo-GTP and 8-oxo-ATP. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA.
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