Anti-RPUSD3 Polyclonal Antibody
Cat: K111730P
Summary:
| 【Product name】：Anti-RPUSD3 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：285367 | 【Swiss Prot】：Q6P087 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000.;IHC 1:100-300. | |
| 【Immunogen】：Recombinant protein of human RPUSD3 | |
| 【Public Immunogen Range】：1-344aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Catalyzes uridine to pseudouridine isomerization (pseudouridylation) of specific mitochondrial mRNAs (mt-mRNAs), a post-transcriptional modification necessary for their translation. Acts at position 390 in COXI mt-mRNA and at position 697-699 in mitochondrial COXIII mt-mRNA (PubMed:27974379). As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and may play a role in mitochondrial ribosome biogenesis.
Verified picture:
Western blot analysis with RPUSD3 antibody diluted at 1:2000;Lane: 293T,PC-3M-IE8,Mouse brain.
Immunohistochemistry of paraffin-embedded Human colorectal cancer with RPUSD3 antibody diluted at 1:200.