Anti-VPS52 Polyclonal Antibody
Cat: K111731P
Summary:
| 【Product name】：Anti-VPS52 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：6293 | 【Swiss Prot】：Q8N1B4 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-3000.;IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human VPS52 | |
| 【Public Immunogen Range】：1-350aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD. Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane.
Verified picture:
Western blot analysis with VPS52 antibody diluted at 1:2000;Lane: PC-3M-IE8,Human liver cancer.
Immunohistochemistry of paraffin-embedded Human colorectal cancer with VPS52 antibody diluted at 1:100.