Anti-MAGEA6 Polyclonal Antibody
Cat: K111733P
Summary:
| 【Product name】：Anti-MAGEA6 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：4105 | 【Swiss Prot】：P43360 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-3000.;IHC 1:100-300. | |
| 【Immunogen】：Recombinant protein of human MAGEA6 | |
| 【Public Immunogen Range】：1-110aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines.
Verified picture:
Western blot analysis with MAGEA6 antibody diluted at 1:2000;Lane: Mouse testis,Mouse brain,Rat brain.
Immunohistochemistry of paraffin-embedded Human testis cancer with MAGEA6 antibody diluted at 1:200.