下载
Anti-MTARC2 Polyclonal Antibody
Cat: K111748P
Summary:
【Product name】:Anti-MTARC2 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:54996 【Swiss Prot】:Q969Z3
【Tested applications】:IHC,WB
【Recommended dilution】:WB 1:1000-3000.;IHC 1:50-200.
【Immunogen】:Recombinant protein of human MTARC2
【Public Immunogen Range】:45-335aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Catalyzes the reduction of N-oxygenated molecules, acting as a counterpart of cytochrome P450 and flavin-containing monooxygenases in metabolic cycles. As a component of prodrug-converting system, reduces a multitude of N-hydroxylated prodrugs particularly amidoximes, leading to increased drug bioavailability. May be involved in mitochondrial N(omega)-hydroxy-L-arginine (NOHA) reduction, regulating endogenous nitric oxide levels and biosynthesis. Postulated to cleave the N-OH bond of N-hydroxylated substrates in concert with electron transfer from NADH to cytochrome b5 reductase then to cytochrome b5, the ultimate electron donor that primes the active site for substrate reduction.
Verified picture:
Western blot analysis with MTARC2 antibody diluted at 1:2000;Lane: Mouse liver,T-47d.
Immunohistochemistry of paraffin-embedded Human endometrial cancer with MTARC2 antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded Human liver cancer with MTARC2 antibody diluted at 1:100.