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Anti-CA12 Polyclonal Antibody - SAlexa Fluor 640
Cat: K111752P - SAlexa Fluor 640
Summary:
【Product name】:Anti-CA12 Polyclonal Antibody - SAlexa Fluor 640 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:771 【Swiss Prot】:O43570
【Tested applications】:IHC
【Recommended dilution】:IHC 1:50-200.
【Immunogen】:Recombinant protein of human CA12
【Public Immunogen Range】:1-142aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Three transcript variants encoding different isoforms have been identified for this gene.
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