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Anti-VCAM1 Polyclonal Antibody - SAlexa Fluor 405
Cat: K111771P - SAlexa Fluor 405
Summary:
【Product name】:Anti-VCAM1 Polyclonal Antibody - SAlexa Fluor 405 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Octanoic acid-ammonium sulfate precipitation
【Gene ID】:7412 【Swiss Prot】:P19320
【Tested applications】:IHC
【Recommended dilution】:IHC 1:50-200.
【Immunogen】:Recombinant protein of human VCAM1
【Public Immunogen Range】:20-370aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
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