Anti-IL23R Polyclonal Antibody - SAlexa Fluor 350
Cat: K111774P - SAlexa Fluor 350
Summary:
| 【Product name】：Anti-IL23R Polyclonal Antibody - SAlexa Fluor 350 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：149233 | 【Swiss Prot】：Q5VWK5 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human IL23R | |
| 【Public Immunogen Range】：1-282aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.
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