Anti-IL23A Polyclonal Antibody - SAlexa Fluor 405
Cat: K111801P - SAlexa Fluor 405
Summary:
| 【Product name】：Anti-IL23A Polyclonal Antibody - SAlexa Fluor 405 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：51561 | 【Swiss Prot】：Q9NPF7 |
| 【Tested applications】：IHC,IF | |
| 【Recommended dilution】：IHC 1:50-200. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human IL23A | |
| 【Public Immunogen Range】：1-170aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
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