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Anti-IL23A Polyclonal Antibody - SAlexa Fluor 568
Cat: K111801P - SAlexa Fluor 568
Summary:
【Product name】:Anti-IL23A Polyclonal Antibody - SAlexa Fluor 568 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:51561 【Swiss Prot】:Q9NPF7
【Tested applications】:IHC,IF
【Recommended dilution】:IHC 1:50-200. IF 1:50-200.
【Immunogen】:Recombinant protein of human IL23A
【Public Immunogen Range】:1-170aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
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