Anti-IZUMO1 Polyclonal Antibody - SAlexa Fluor 555
Cat: K111827P - SAlexa Fluor 555
Summary:
| 【Product name】：Anti-IZUMO1 Polyclonal Antibody - SAlexa Fluor 555 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：284359 | 【Swiss Prot】：Q8IYV9 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human IZUMO1 | |
| 【Public Immunogen Range】：1-351aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg (PubMed:15759005). The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion (PubMed:15759005). The ligand-receptor interaction probably does not act as a membrane 'fusogen' (PubMed:15759005).
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