Anti-TRPM1 Polyclonal Antibody
Cat: K111846P
Summary:
| 【Product name】：Anti-TRPM1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：4308 | 【Swiss Prot】：Q7Z4N2 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human TRPM1 | |
| 【Public Immunogen Range】：1-137aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a member of the transient receptor potential melastatin subfamily of transient receptor potential ion channels. The encoded protein is a calcium permeable cation channel that is expressed in melanocytes and may play a role in melanin synthesis. Specific mutations in this gene are the cause autosomal recessive complete congenital stationary night blindness-1C. The expression of this protein is inversely correlated with melanoma aggressiveness and as such it is used as a prognostic marker for melanoma metastasis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]
Verified picture:
Immunohistochemistry of paraffin-embedded Mouse lung with TRPM1 antibody diluted at 1:100.