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Anti-GPR125 Polyclonal Antibody - SAlexa Fluor 568
Cat: K010000P - SAlexa Fluor 568
Summary:
【Product name】:Anti-GPR125 Polyclonal Antibody - SAlexa Fluor 568 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:166647 【Swiss Prot】:Q8IWK6
【Tested applications】:ELISA,FCM,IF,ICC,IHC,WB
【Recommended dilution】:WB 1:500-2000. ELISA 1:5000-10000. IHC 1:100-500. FCM 1μg/Test. ICC 1:100-500. IF 1:100-500.
【Immunogen】:A synthetic peptide of human GPR125
【Public Immunogen Range】:422-530/1321aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR125 (G protein-coupled receptor 125), also known as PGR21 or TEM5L, is a 1,321 amino acid multi-pass membrane protein belonging to the G-protein coupled receptor 2 family and the LN-TM7 subfamily. Considered a novel orphan adhesion-type G-protein-coupled receptor, GPR125 has five leucine rich repeats (LRR), an immunoglobulin (Ig) domain and a GPS domain. GPR125 may play a functional role in choroidal and hippocampal response to brain injury. It is also suggested that GPR125 may be a marker for spermatogonial stem cells. Four isoforms of GPR125 exists due to alternative splicing events.
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