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Anti-CDH13 Polyclonal Antibody - SAlexa Fluor 350
Cat: K111879P - SAlexa Fluor 350
Summary:
【Product name】:Anti-CDH13 Polyclonal Antibody - SAlexa Fluor 350 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:1012 【Swiss Prot】:P55290
【Tested applications】:ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:A synthetic peptide of human CDH13
【Public Immunogen Range】:345-395/713aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
This gene encodes a member of the cadherin superfamily. The encoded protein is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. The protein lacks the cytoplasmic domain characteristic of other cadherins, and so is not thought to be a cell-cell adhesion glycoprotein. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.
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