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Anti-BMPR2 Polyclonal Antibody - FITC
Cat: K111943P - FITC
Summary:
【Product name】:Anti-BMPR2 Polyclonal Antibody - FITC 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:659 【Swiss Prot】:Q13873
【Tested applications】:ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human BMPR2
【Public Immunogen Range】:600-950aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6.
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