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Anti-UBASH3B Polyclonal Antibody - SAlexa Fluor 647
Cat: K112002P - SAlexa Fluor 647
Summary:
【Product name】:Anti-UBASH3B Polyclonal Antibody - SAlexa Fluor 647 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:84959 【Swiss Prot】:Q8TF42
【Tested applications】:FC ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human UBASH3B
【Public Immunogen Range】:1-350aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface. Exhibits tyrosine phosphatase activity toward several substrates including EGFR, FAK, SYK, and ZAP70. Down-regulates proteins that are dually modified by both protein tyrosine phosphorylation and ubiquitination.
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