下载
Anti-ABCA8 Polyclonal Antibody - SAlexa Fluor 350
Cat: K112092P - SAlexa Fluor 350
Summary:
【Product name】:Anti-ABCA8 Polyclonal Antibody - SAlexa Fluor 350 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:10351 【Swiss Prot】:O94911
【Tested applications】:ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human ABCA8
【Public Immunogen Range】:60-215aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Catalyzes the import of organic anions such as taurocholate and estrone sulfate in an ATP-dependent manner (PubMed:12379217).In vitro, also imports ochratoxin A (PubMed:12379217).In addition mediates the cholesterol efflux in an apolipoprotein independent manner an plays a role in sphingomyelin production in oligodendrocytes (PubMed:23560799).Catalyzes the cholesterol and taurocholate efflux in an ATP-dependent manner (PubMed:29300488).Through the interaction with ABCA1 potentiates the cholesterol efflux to lipid-free APOA1, in turn regulates high-density lipoprotein cholesterol levels (PubMed:28882873).
Verified picture: