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Anti-GLA Polyclonal Antibody - SAlexa Fluor 405
Cat: K112097P - SAlexa Fluor 405
Summary:
【Product name】:Anti-GLA Polyclonal Antibody - SAlexa Fluor 405 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:2717 【Swiss Prot】:P06280
【Tested applications】:IHC
【Recommended dilution】:IHC 1:50-200.
【Immunogen】:Recombinant protein of human GLA
【Public Immunogen Range】:1-350aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.
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