Anti-IL-2 Polyclonal Antibody - SAlexa Fluor 640
Cat: K010028P - SAlexa Fluor 640
Summary:
| 【Product name】：Anti-IL-2 Polyclonal Antibody - SAlexa Fluor 640 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3558 | 【Swiss Prot】：P60568 |
| 【Observed】：15KDa/16KDa/18KDa | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-1000. IHC 1:50-200. | |
| 【Immunogen】：Recombinant fusion protein of human IL-2 | |
| 【Public Immunogen Range】：21-153aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.
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