Anti-TNS2 Polyclonal Antibody - Cy7
Cat: K112174P - Cy7
Summary:
| 【Product name】：Anti-TNS2 Polyclonal Antibody - Cy7 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：23371 | 【Swiss Prot】：Q63HR2 |
| 【Observed】：180kDa | |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-3000. | |
| 【Immunogen】：A synthetic peptide of Human TNS2 | |
| 【Public Immunogen Range】：860-910/1409aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Tyrosine-protein phosphatase which regulates cell motility proliferation and muscle-response to insulin (PubMed:15817639, PubMed:23401856). In muscles and under catabolic conditions, dephosphorylates IRS1 leading to its degradation and muscle atrophy (PubMed:23401856). Negatively regulates PI3K-AKT pathway activation (PubMed:15817639, PubMed:23401856)
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