Anti-OTUB1 Polyclonal Antibody - RBITC
Cat: K112328P - RBITC
Summary:
| 【Product name】：Anti-OTUB1 Polyclonal Antibody - RBITC | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：55611 | 【Swiss Prot】：Q96FW1 |
| 【Observed】：34kDa | |
| 【Tested applications】：WB ELISA IHC ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human OTUB1 | |
| 【Public Immunogen Range】：1-272aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants.
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