Anti-Phospho-Beclin 1-Ser15 Polyclonal Antibody - SAlexa Fluor 555
Cat: K010025P - SAlexa Fluor 555
Summary:
| 【Product name】：Anti-Phospho-Beclin 1-Ser15 Polyclonal Antibody - SAlexa Fluor 555 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：8678 | 【Swiss Prot】：Q14457 |
| 【Observed】：60kDa | |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic phosphorylated peptide around S15 of human Beclin 1 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.
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