PMP22 Antibody Blocking Peptide

This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Studies suggest two alternately used promoters drive tissue-specific expression. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA， Dejerine-Sottas syndrome， and hereditary neuropathy with liability to pressure palsies. Alternative splicing results in multiple transcript variants.