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SDHB Antibody Blocking Peptide

Cat:K107471P-Ag

Summary:

【Derived From】: Synthetic
【Uniprot】: P21912
【Gene ID】: 6390
【Application】: Blocking Peptide of K107471P Antibody
【Purification】: HPLC
【Bioactive】: Not tested

Store:

【Storage】: Store at -20℃,2 years.Avoid freeze/thaw cycles.
【Formulation】: Lyophilized powder

Background:

Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.

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