YWHAH Antibody Blocking Peptide

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals， and this protein is 99% identical to the mouse， rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5’ UTR， and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder.