Summary:
GPR31 Antibody Blocking Peptide
Cat：K107791P-Ag
| 【Derived From】： Synthetic |
| 【Uniprot】： O00270 |
| 【Gene ID】： 2853 |
| 【Application】： Blocking Peptide of K107791P Antibody |
| 【Purification】： HPLC |
| 【Bioactive】： Not tested |
Store:
| 【Storage】： Store at -20℃，2 years.Avoid freeze/thaw cycles. |
| 【Formulation】： Lyophilized powder |
Background:
High-affinity receptor for 12-(S)-hydroxy-5，8，10，14-eicosatetraenoic acid (12-S-HETE). 12-(S)-HETE is an arachidonic acid metabolite secreted by platelets and tumor cells， and known to induce endothelial cells retraction allowing invasive cell access to the subendothelial matrix， which is a critical step for extravasation or metastasis. Ligand-binding lead to activation of ERK1/2 (MAPK3/MAPK1)， MEK， and NF-kappa-B.
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