Summary:
NFATC2IP Antibody Blocking Peptide
Cat：K108447P-Ag
| 【Derived From】： Synthetic |
| 【Uniprot】： Q8NCF5 |
| 【Gene ID】： 84901 |
| 【Application】： Blocking Peptide of K108447P Antibody |
| 【Purification】： HPLC |
| 【Bioactive】： Not tested |
Store:
| 【Storage】： Store at -20℃，2 years.Avoid freeze/thaw cycles. |
| 【Formulation】： Lyophilized powder |
Background:
In T-helper 2 (Th2) cells， regulates the magnitude of NFAT-driven transcription of a specific subset of cytokine genes， including IL3， IL4， IL5 and IL13， but not IL2. Recruits PRMT1 to the IL4 promoter; this leads to enhancement of histone H4 ’Arg-3’-methylation and facilitates subsequent histone acetylation at the IL4 locus， thus promotes robust cytokine expression. Down-regulates formation of poly-SUMO chains by UBE2I/UBC9.
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