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PKMYT1 Antibody Blocking Peptide

Cat:K108707P-Ag

Summary:

【Derived From】: Synthetic
【Uniprot】: Q99640
【Gene ID】: 9088
【Application】: Blocking Peptide of K108707P Antibody
【Purification】: HPLC
【Bioactive】: Not tested

Store:

【Storage】: Store at -20℃,2 years.Avoid freeze/thaw cycles.
【Formulation】: Lyophilized powder

Background:

Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on ’Thr-14’. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on ’Tyr-15’ to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development.

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