ILK Antibody Blocking Peptide

This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins， where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition， and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants.