ITPKA Antibody Blocking Peptide

Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1，4，5-trisphosphate to Ins(1，3，4，5)P4. The activity of the inositol 1，4，5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase， calcium/calmodulin- dependent protein kinase II， and protein kinase C in vitro.