Summary:
TMEM106A Antibody Blocking Peptide
Cat：K109436P-Ag
| 【Derived From】： Synthetic |
| 【Uniprot】： Q96A25 |
| 【Gene ID】： 113277 |
| 【Application】： Blocking Peptide of K109436P Antibody |
| 【Purification】： HPLC |
| 【Bioactive】： Not tested |
Store:
| 【Storage】： Store at -20℃，2 years.Avoid freeze/thaw cycles. |
| 【Formulation】： Lyophilized powder |
Background:
Activates macrophages and polarizes them into M1-like macrophages through the activation of the MAPK and NF-kappaB signaling pathway. Upon activation， upregulates the expression of CD80， CD86， CD69 and MHC II on macrophages， and induces the release of pro-inflammatory cytokines such as TNF， IL1B， IL6， CCL2 and nitric oxide. May play a role in inhibition of proliferation and migration.
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