DAB1 Antibody Blocking Peptide

The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice， the disabled-1 gene plays a central role in brain development， directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1， and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain.