Summary:
SCN9A Antibody Blocking Peptide
Cat：K110412P-Ag
| 【Derived From】： Synthetic |
| 【Amino Acid】： 1938-1988/1988aa |
| 【Uniprot】： Q15858 |
| 【Gene ID】： 6335 |
| 【Application】： Blocking Peptide of K110412P Antibody |
| 【Purification】： HPLC |
| 【Bioactive】： Not tested |
Store:
| 【Storage】： Store at -20℃，2 years.Avoid freeze/thaw cycles. |
| 【Formulation】： Lyophilized powder |
Background:
Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane， the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient (PubMed:7720699， PubMed:17167479， PubMed:25240195， PubMed:26680203， PubMed:15385606， PubMed:16988069， PubMed:17145499， PubMed:19369487， PubMed:24311784). It is a tetrodotoxin-sensitive Na+ channel isoform (PubMed:7720699). Plays a role in pain mechanisms， especially in the development of inflammatory pain (PubMed:17167479， PubMed:17145499， PubMed:19369487， PubMed:24311784).
Verified picture
