Summary:
CASP10 Antibody Blocking Peptide
Cat：K110451P-Ag
| 【Derived From】： Synthetic |
| 【Amino Acid】： 205-255/521aa |
| 【Uniprot】： Q92851 |
| 【Gene ID】： 843 |
| 【Application】： Blocking Peptide of K110451P Antibody |
| 【Purification】： HPLC |
| 【Bioactive】： Not tested |
Store:
| 【Storage】： Store at -20℃，2 years.Avoid freeze/thaw cycles. |
| 【Formulation】： Lyophilized powder |
Background:
Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase-3， -4， -6， -7， -8， and -9. Hydrolyzes the small- molecule substrates， Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC.1 Publication Isoform 7 can enhance NF-kappaB activity but promotes only slight apoptosis.Isoform C is proteolytically inactive.
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