Summary:
MRTFA Antibody Blocking Peptide
Cat：K110461P-Ag
| 【Derived From】： Synthetic |
| 【Amino Acid】： 755-805/931aa |
| 【Uniprot】： Q969V6 |
| 【Gene ID】： 57591 |
| 【Application】： Blocking Peptide of K110461P Antibody |
| 【Purification】： HPLC |
| 【Bioactive】： Not tested |
Store:
| 【Storage】： Store at -20℃，2 years.Avoid freeze/thaw cycles. |
| 【Formulation】： Lyophilized powder |
Background:
Transcription coactivator that associates with the serum response factor (SRF) transcription factor to control expression of genes regulating the cytoskeleton during development， morphogenesis and cell migration. The SRF-MRTFA complex activity responds to Rho GTPase-induced changes in cellular globular actin (G-actin) concentration， thereby coupling cytoskeletal gene expression to cytoskeletal dynamics. MRTFA binds G-actin via its RPEL repeats， regulating activity of the MRTFA-SRF complex. Activity is also regulated by filamentous actin (F-actin) in the nucleus.
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