Summary:
DHRS2 Antibody Blocking Peptide
Cat：K110462P-Ag
| 【Derived From】： Synthetic |
| 【Amino Acid】： 175-225/280aa |
| 【Uniprot】： Q13268 |
| 【Gene ID】： 10202 |
| 【Application】： Blocking Peptide of K110462P Antibody |
| 【Purification】： HPLC |
| 【Bioactive】： Not tested |
Store:
| 【Storage】： Store at -20℃，2 years.Avoid freeze/thaw cycles. |
| 【Formulation】： Lyophilized powder |
Background:
Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3，4-Hexanedione， 2，3-Heptanedione and 1-Phenyl-1，2-propanedione as substrates. No reductase activity is displayed in vitro with steroids， retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation， leading to p53/TP53 stabilization and increased transcription activity， resulting in the accumulation of MDM2 and CDKN1A/p21.
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