Summary:
MUC1 Antibody Blocking Peptide
Cat：K110468P-Ag
| 【Derived From】： Synthetic |
| 【Amino Acid】： 105-155/1255aa |
| 【Uniprot】： P15941 |
| 【Gene ID】： 4582 |
| 【Application】： Blocking Peptide of K110468P Antibody |
| 【Purification】： HPLC |
| 【Bioactive】： Not tested |
Store:
| 【Storage】： Store at -20℃，2 years.Avoid freeze/thaw cycles. |
| 【Formulation】： Lyophilized powder |
Background:
The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack.
The beta subunit contains a C-terminal domain which is involved in cell signaling， through phosphorylations and protein-protein interactions. Modulates signaling in ERK， SRC and NF-kappa-B pathways. In activated T-cells， influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds， together with KLF4， the PE21 promoter element of TP53 and represses TP53 activity.
The beta subunit contains a C-terminal domain which is involved in cell signaling， through phosphorylations and protein-protein interactions. Modulates signaling in ERK， SRC and NF-kappa-B pathways. In activated T-cells， influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds， together with KLF4， the PE21 promoter element of TP53 and represses TP53 activity.
Verified picture
