Summary:
GNL3L Antibody Blocking Peptide
Cat：K110672P-Ag
| 【Derived From】： Synthetic |
| 【Amino Acid】： 1-51/582aa |
| 【Uniprot】： Q9NVN8 |
| 【Gene ID】： 54552 |
| 【Application】： Blocking Peptide of K110672P Antibody |
| 【Purification】： HPLC |
| 【Bioactive】： Not tested |
Store:
| 【Storage】： Store at -20℃，2 years.Avoid freeze/thaw cycles. |
| 【Formulation】： Lyophilized powder |
Background:
Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis， promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination， and hence proteasomal degradation. By acting on MDM2， may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP.
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