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MFNG Antibody Blocking Peptide

Cat:K110808P-Ag

Summary:

【Derived From】: Synthetic
【Amino Acid】: 271-321/321aa
【Uniprot】: O00587
【Gene ID】: 4242
【Application】: Blocking Peptide of K110808P Antibody
【Purification】: HPLC
【Bioactive】: Not tested

Store:

【Storage】: Store at -20℃,2 years.Avoid freeze/thaw cycles.
【Formulation】: Lyophilized powder

Background:

Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules (PubMed:10935626). Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1 (By similarity).

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