RACGAP1 Antibody Blocking Peptide

This gene encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis， which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis， cell growth， and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on chromosome 12.